Two pre-existing routes, the A5127 Lichfield Road, which runs roughly parallel to the Aston Expressway, and the A38 Tyburn Road, which runs roughly parallel to the M6, were also added to the junction.

Three minor roads, Copeley Hill, Minstead Road and Slade Road, were also added.

The junction covers a 30-acre site and is partially elevated on concrete columns.

Slip roads in both directions join each of the 4 inter-connected high-speed routes and dual-carriage service roads carry traffic between the slip roads; the minor roads are connected to the A-roads at Salford Circus.

Spaghetti Junction stands at the convergence of 3 river valleys: the Rea, Tame, and Hockley Brook.

It bridges the Cross City Railway, Salford Canal Junction, Birmingham and Fazeley Canal, Tame Valley Canal and Birmingham and Warwick Junction Branch Canal.

Many power and communications lines run beneath Spaghetti Junction which was a Soviet nuclear target during the Cold War.