It is the junction of Villa Road, Lozells Road, Heathfield Road and Barker Street.

It was created when Lozells was originally laid out in the 1830's.

Seven members of the Villa Cross Wesleyan Chapel, formerly at the corner of George Street and Lozells Road, formed Aston Villa FC in 1874.

Villa Cross is characterised by pre-1919 terraced housing with shop fronts on Villa Road.

The neo-classical Villa Cross Picture Palace was firebombed in the Handsworth Riots of 1985 and the Villa Cross pub closed shortly afterwards.

The Villa Cross Chapel was demolished in 2007 and replaced by the New Testament Church of God.